Original Coverage: Genetic Twist Behind Orange Cat Fur Finally Uncovered

Researchers from Kyushu University, Japan, have found the X-linked mutation behind orange fur in house cats. This mutation increases gene activity in pigment-producing skin cells, shifting fur color toward orange. Discovery explains why most orange cats are male and why females with one copy of the gene develop calico or tortoiseshell coats. Study suggests the orange gene may influence more than just coat color, with possible effects on brain and hormonal activity. The findings are confirmed by a second independent study by researchers at Stanford University, U.S., with both papers publishing simultaneously in Current Biology on May 15, 2025. The study was published in the journal Current Biology, which is published by the University of California, San Francisco, on behalf of the Japan Institute of Bioregulation and the Institute for Advanced Study in Japan. For confidential support call the Samaritans on 08457 90 90 90, visit a local Samaritans branch or see www.samaritans.org for details. In the United States, call the National Suicide Prevention Line on 1-800-273-8255.

Source: Neurosciencenews.com  |  Read full article