The Boston Red Sox are set to play the Chicago Cubs at Wrigley Field. The game will take place on Saturday, July 19, 2025, at 7:15 PM. Fans can catch the action on FOX.

The Red Sox, managed by Alex Cora, have a 53-46 record this season. They are 4 games behind in the AL East. On the other side, the Cubs, led by Craig Counsell, hold a 58-39 record. They have a strong home record of 31-16. The weather forecast indicates a warm night with light rain and a breeze.

Red Sox vs Cubs Key Information

Sport: Baseball

Teams: Boston Red Sox vs. Chicago Cubs

Venue: Wrigley Field in Chicago, IL

Date: Saturday, July 19, 2025

Betting Odds: Red Sox Moneyline +126, Cubs Moneyline -149, Red Sox Runline +1.5 (-157), Cubs Runline -1.5 (+131), Total Over 9.0 (-107), Total Under 9.0 (-114)

The Red Sox Can Win If…

The Boston Red Sox recently played against the Chicago Cubs, ending with a 4-1 loss. Despite the loss, the Red Sox managed seven hits, with Marcelo Mayer leading the way with two singles. Starting pitcher Lucas Giolito had a challenging outing, allowing four earned runs over 5 1/3 innings, but he also struck out six batters.

Boston’s offense has been strong this season, with a team batting average of .255, ranking fourth in the league. They lead the league in doubles with 201, showing their ability to hit for power. The Red Sox also have a solid slugging percentage of .431, which is fourth in the league, indicating they can score runs quickly.

Brayan Bello will start for the Red Sox, bringing an ERA of 3.14 and a record of 6-3. He has shown consistency on the mound and can keep the game close. With hitters like Trevor Story and Alex Bregman, who have been productive, the Red Sox have the potential to win this game.

The Cubs Can Win If…

The Chicago Cubs are coming off a strong 4-1 win against the Boston Red Sox. In that game, Seiya Suzuki stood out with a home run and three RBIs. Colin Rea pitched five solid innings, allowing only one run, which set the tone for the Cubs’ victory.

The Cubs have been performing well this season, with a batting average of .255, ranking them 4th in the league. Their slugging percentage is even more impressive at .445, placing them 2nd. With 143 home runs, they hold the 3rd spot in the league, showing their power at the plate.

Shota Imanaga will start for the Cubs with an ERA of 2.65 and WHIP of 0.93. His strong pitching can keep the Red Sox hitters in check. The Cubs have also been effective in avoiding blown saves, leading the league with only ten, which could be crucial in close games.

The Lean

The Cubs are favored with a moneyline of -149. The Red Sox have a moneyline of +126. Given the Cubs’ strong slugging percentage, ranked 2nd in the league, and their home advantage, the recommendation is to pick the Cubs to win. The model projects a score of Cubs 5, Red Sox 4.

The total for the game is set at 9.0 runs, with the over at -107 and the under at -114. Both teams have solid hitting stats, with the Red Sox leading in doubles. The model projects a total of 9 runs, aligning with the set line. The recommendation is to take the over, as both teams have the potential to score well.

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Streaking Cubs Look to Continue Momentum Against Red Sox

One long winning streak ended on Friday night at Wrigley Field. Now, the Chicago Cubs will look to extend their own. The first-place Chicago Cubs will aim for their fifth straight victory on Saturday as they continue their marquee interleague series against the visiting Boston Red Sox.

The Suzuki Show

The Cubs’ 4-1 victory in the series opener, which snapped Boston’s 10-game winning streak, was powered by their star right fielder, Seiya Suzuki. Apparently fueled by a recent All-Star snub, Suzuki hit a go-ahead, three-run homer that proved to be the difference. He now leads the National League with 80 RBIs.

“Seiya is having a tremendous offensive season,” Cubs manager Craig Counsell said. “You put men on base in front of him and good things seem to happen this year.”

Starting a New Streak

While the Red Sox were disappointed to see their streak end, they are focused on bouncing back immediately. A key baserunning mistake in the fifth inning on Friday cost them a chance at a rally, a mistake the player took full responsibility for.

“I’ve got to put the blame on me,” said Abraham Toro. “Being thrown out in a double play kills rallies. Just have to learn from it and go again tomorrow.”

A Duel of Aces

Saturday’s game features a fantastic pitching matchup between two of the hottest right-handers in baseball. The Cubs will send out their ace, Shota Imanaga (6-3, 2.65 ERA). The left-hander has been dominant since returning from the injured list, posting a 2.31 ERA in his last four starts.

The Red Sox will counter with their own hot hand in Brayan Bello (6-3, 3.14). Bello is on a three-start personal winning streak and has a 2.21 ERA in the month of July. This premier duel will be the main event on the scores and odds board.

A Playoff Atmosphere

This series is a clash between two first-place MLB teams and could be a potential World Series preview. The intensity of these matchups is a key topic in our expert betting guide. To see which ace our experts think will lead his team to victory, check out our daily MLB picks.

Boston Red Sox (53-47, third in the AL East) vs. Chicago Cubs (59-39, first in the NL Central)

Chicago; Sunday, 2:20 p.m. EDT

PITCHING PROBABLES: Red Sox: Garrett Crochet (10-4, 2.23 ERA, 1.04 WHIP, 160 strikeouts); Cubs: Cade Horton (3-3, 4.45 ERA, 1.41 WHIP, 43 strikeouts)

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BETMGM SPORTSBOOK LINE: Red Sox -140, Cubs +117; over/under is 7 runs

BOTTOM LINE: The Chicago Cubs host the Boston Red Sox trying to extend a three-game home winning streak.

Chicago has a 59-39 record overall and a 32-16 record in home games. The Cubs are 45-7 in games when they out-hit their opponents.

Boston has a 21-27 record on the road and a 53-47 record overall. The Red Sox have the sixth-ranked team ERA in the AL at 3.83.

The teams meet Sunday for the third time this season.

TOP PERFORMERS: Pete Crow-Armstrong leads the Cubs with 26 home runs while slugging .551. Carson Kelly is 11 for 32 with three home runs and seven RBIs over the past 10 games.

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Wilyer Abreu has 11 doubles and 18 home runs for the Red Sox. Ceddanne Rafaela is 15 for 37 with three doubles and five home runs over the last 10 games.

LAST 10 GAMES: Cubs: 6-4, .251 batting average, 3.72 ERA, outscored opponents by 11 runs

Red Sox: 8-2, .272 batting average, 2.56 ERA, outscored opponents by 21 runs

INJURIES: Cubs: Porter Hodge: 15-Day IL (shoulder), Jameson Taillon: 15-Day IL (calf), Miguel Amaya: 10-Day IL (oblique), Eli Morgan: 60-Day IL (elbow), Javier Assad: 60-Day IL (oblique), Justin Steele: 60-Day IL (elbow)

Red Sox: Hunter Dobbins: 15-Day IL (acl), Nick Burdi: 60-Day IL (knee), Liam Hendriks: 60-Day IL (hip), Zack Kelly: 15-Day IL (oblique), Justin Slaten: 60-Day IL (shoulder), Luis Guerrero: 15-Day IL (elbow), Josh Winckowski: 60-Day IL (elbow), Triston Casas: 60-Day IL (knee), Kutter Crawford: 60-Day IL (knee), Tanner Houck: 15-Day IL (flexor), Patrick Sandoval: 60-Day IL (elbow)

___

The Associated Press created this story using technology provided by Data Skrive and data from Sportradar.

The Associated Press

Jul 19, 2025; Chicago, Illinois, USA; Chicago Cubs pitcher Shota Imanaga (18) throws the ball during the fifth inning against the Boston Red Sox at Wrigley Field. David Banks-Imagn Images Purchase Licensing Rights , opens new tab

Item 1 of 5 Jul 19, 2025; Chicago, Illinois, USA; Chicago Cubs pitcher Shota Imanaga (18) throws the ball during the fifth inning against the Boston Red Sox at Wrigley Field. David Banks-Imagn Images

July 20 – Isaac Collins and Joey Ortiz hit home runs, William Contreras added a two-run double, and the visiting Milwaukee Brewers extended their winning streak to a season-best nine games while remaining perfect against the Los Angeles Dodgers with an 8-7 victory on Saturday.

The Brewers won even as All-Star right-hander Freddy Peralta (12-4) tied a season high by allowing four runs in five innings. Trevor Megill pitched the ninth inning for his 23rd save as Milwaukee improved to 5-0 against Los Angeles with the finale of the season series Sunday.

Neither team has swept the other in a season series since the Brewers moved to the National League in 1998.

Shohei Ohtani hit one of three home runs for the Dodgers, who have lost nine of their last 11 games. With a struggling Mookie Betts getting the night off for Los Angeles, Will Smith had two hits out of the No. 2 spot of the lineup.

Yankees 12, Braves 9

Trent Grisham hit his third career grand slam in the ninth inning to propel visiting New York to a come-from-behind win over Atlanta.

Grisham hit a slider from Raisel Iglesias into the right field seats to give the Yankees their first lead of the game and help end their three-game losing streak. It was Grisham’s 17th homer, tying his career high. Luke Weaver pitched 1 2/3 scoreless innings and earned the win. Anthony Volpe sparked the New York offense with a pair of home runs, his 11th and 12th, and a sacrifice fly.

The Braves had built a 5-0 lead thanks in part to a 438-foot solo homer by Michael Harris II, his first since June 13, and a three-run homer by Ozzie Albies. Albies added a two-run single in the fifth to give Atlanta a 7-2 lead before New York’s rally.

Cubs 6, Red Sox 0

Shota Imanaga threw seven scoreless innings, and Michael Busch and Kyle Tucker slugged back-to-back home runs in the first as Chicago blanked visiting Boston.

Imanaga (7-3) allowed just five hits while striking out five and walking one, helping the Cubs take the weekend series and win their fourth straight game. Matt Shaw, Pete Crow-Armstrong and Ian Happ each added solo homers for Chicago, which now holds the majors’ best record (59-39).

Boston starter Brayan Bello (6-4) allowed three runs on six hits in the loss, striking out four and walking one. The Red Sox have lost two straight after posting a 10-game winning streak to end the first half.

Reds 5, Mets 2

Jake Fraley matched a season high with three hits, including a go-ahead RBI single, as Cincinnati rallied from an early two-run deficit to win in New York.

Fraley had two doubles and Spencer Steer added two hits for the Reds, who won for the sixth time in seven games to improve to a season-high five games over .500.

Brett Baty homered and singled for New York, while Luis Torrens added two hits. Mark Vientos also singled and drove in a run.

Marlins 3, Royals 1

Shortstop Otto Lopez drove in all three runs as host Miami defeated Kansas City.

Lopez’s two-run double in the eighth inning snapped a 1-1 score. Xavier Edwards added a triple, a double and two runs scored as the Marlins improved to 21-10 over their past 31 games. Miami’s Cal Quantrill pitched a season-high six innings, allowing two hits (both singles), no walks and no runs while striking out three. Ronny Henriquez (6-1) earned the win, and Anthony Bender pitched a scoreless ninth, earning his third save.

Reliever Lucas Erceg (4-3) took the loss for the Royals after Michael Wacha pitched six innings, allowing three hits, one walk and one run with one strikeout. Salvador Perez led the Royals at the plate with a homer.

Blue Jays 6, Giants 3

Eric Lauer pitched six strong innings, Tyler Heineman had a homer and three RBIs and host Toronto defeated San Francisco.

Lauer (5-2) allowed two runs, two hits and no walks with seven strikeouts. Addison Barger was 4-for-4 for the Blue Jays, who have won the first of two games of the three-game series. Will Wagner had a two-run double for the second game in a row for Toronto, which had a 14-4 advantage in hits on Saturday.

Willy Adames hit two solo home runs for the Giants. Starter Logan Webb (9-7) completed six innings, allowing four runs, 11 hits and one walk with one strikeout.

Phillies 9, Angels 5

Kyle Schwarber belted a go-ahead grand slam in the sixth inning to vault Philadelphia to a home win over Los Angeles.

Bryce Harper also homered for the Phillies after hitting two bombs in Friday’s 6-5 defeat in the series opener. Nick Castellanos, Trea Turner and Johan Rojas drove in the other runs for Philadelphia. Phillies starter Taijuan Walker allowed three runs and nine hits over four innings before handing the ball over to the bullpen.

Taylor Ward, Jo Adell and Yoan Moncada hit home runs for the Angels. Yusei Kikuchi allowed two runs and five hits over five innings before the Los Angeles bullpen scuffled to the finish line.

Rays 4, Orioles 3

Tampa Bay came from behind with a three-run eighth inning — sparked by excellent baserunning — to beat visiting Baltimore.

After tying the game with a single, Chandler Simpson stole his 27th base and went to third on a wild pitch as Jose Caballero walked. Caballero promptly stole his league-leading 32nd base — and the Rays’ third steal of the inning — to put runners at second and third with one out, and both runners would come in to score.

Seranthony Dominguez (2-3) took the loss after giving up three runs (two earned) in 1/3 of an inning in the eighth. Edwin Uceta (6-2) picked up the win with two innings of scoreless relief. Pete Fairbanks earned his 16th save despite giving up a run in the ninth.

White Sox 10, Pirates 4

Mike Tauchman’s go-ahead, bases-clearing double highlighted a six-run sixth inning that propelled Chicago to a comeback win over host Pittsburgh.

Tauchman and Lenyn Sosa each had three RBIs to lead the White Sox to their second win in a row following the All-Star break and their third win in the past five games. After Chicago starter Adrian Houser gave up four runs (three earned) in 4 1/3 innings, the White Sox bullpen held the Pirates scoreless the rest of the way.

The Pirates, who lost their second in a row and have lost 10 of their last 11 games, led 3-0 and rookie starter Mike Burrows took a no-hitter into the fifth inning. After Burrows left the game following the fifth, Caleb Ferguson (2-2) gave up four runs on four hits and recorded only one out.

Rangers 4, Tigers 1

Rowdy Tellez hit a three-run home run to back a strong start by Kumar Rocker as Texas defeated struggling Detroit in the second of three-game series in Arlington, Texas.

Tellez’s homer was a boon for Rocker (4-4), who allowed one hit, walked three and struck out six over 6 1/3 innings of work. Tellez, who was signed to a minor league contract on July 5 by the Rangers a week after being released by Seattle, wasn’t on the team until Friday, when he went 0-for-3.

The Tigers did not get a runner past second base until a Riley Greene home run to open the ninth inning. Detroit starter Keider Montero (4-2) went 4 1/3 innings, giving up four runs on four hits with three walks and five strikeouts.

Diamondbacks 10, Cardinals 1

Eugenio Suarez hit two home runs and drove in three and Corbin Carroll had three hits, including two triples, as host Arizona topped St. Louis to win its third straight game.

Geraldo Perdomo had three singles and four RBIs and Ryne Nelson gave up one run in six innings for the D-backs, who have outscored the Cardinals 17-4 in the first two games of the series. Nelson (6-2) gave up four hits, with Alec Burleson’s homer in the sixth the only damage. Nelson is 4-0 with a 2.29 ERA in his last seven starts. Suarez has 33 homers and leads the NL with 81 RBIs. Carroll leads the majors with 12 triples.

Masyn Winn had three hits for the Cardinals, who have lost 10 of 14. Sonny Gray (9-4) gave up 11 hits and a career-high nine runs (eight earned) before leaving in the fourth.

Athletics 8, Guardians 2

Shea Langeliers and Jacob Wilson both hit two-run home runs and Luis Severino earned his first win in more than a month as the Athletics scored the final eight runs of the game to win in Cleveland.

Severino (3-11) went five innings, allowing two runs on three hits in snapping a five-start losing streak. The right-hander struck out three and walked two in an 86-pitch outing. Jack Perkins and Justin Sterner combined for four hitless innings to wrap up the three-hitter.

Rookie first baseman Kurtz went 3-for-5 and drove in two runs, and speedy center fielder Denzel Clarke fell a homer shy of hitting for the cycle for the Athletics. The Guardians lost for just the second time in nine games.

Rockies 10, Twins 6

Ryan McMahon, Ezequiel Tovar and Hunter Goodman homered as host Colorado rallied to beat Minnesota in Denver to clinch the Rockies’ first home series win of the season.

Tovar was 3-for-4 with two runs scored and three RBIs, and Goodman also drove in three runs. Kody Clemens was 2-for-4 (double, triple) with three RBIs in the loss, the Twins’ third straight.

Rockies starter Antonio Senzatela (4-13) earned the win after allowing three runs and six hits in seven innings with a walk and three strikeouts. Minnesota starter Zebby Matthews (1-2) gave up five runs and eight hits in four-plus innings with a walk and six strikeouts in taking the loss.

Nationals 4, Padres 2

Mitchell Parker tossed six solid innings and Nathaniel Lowe homered to help host Washington double up San Diego and snap a five-game losing streak.

Drew Millas added a two-run single for Washington, which won for just the second time in its past 11 contests. Parker (6-10) allowed two runs on five hits over six innings. He struck out four and walked one while winning for the first time since beating the Padres in San Diego on June 23.

Luis Arraez and Jose Iglesias each had two hits for San Diego, which lost for just the second time in the past six games. Padres starter Yu Darvish (0-2) gave up three runs on five hits over five innings. He struck out one and walked one.

Mariners 7, Astros 6 (11 inn.)

Rookie Cole Young singled home the winning run in the bottom of the 11th inning as Seattle defeated visiting Houston for the Mariners’ fifth straight win.

With Dominic Canzone the runner at second to start the inning, Miles Mastrobuoni put down a sacrifice bunt to move Canzone to third. Young lined a single down the right field line off Houston’s Hector Neris (3-2) to win it.

Both teams scored in the 10th. Houston pinch hitter Taylor Trammell’s sacrifice fly brought home the go-ahead run in the top of the inning. The Mariners tied it in the bottom half as Cal Raleigh scored from third on a fluke groundout off the knob of Dylan Moore’s bat.

–Field Level Media

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A baserunning mistake by Abraham Toro proved crucial in the Sox’ first loss since July 2. With Boston trailing by two runs in the fifth, Toro was doubled off at second base by center fielder Pete Crow-Armstrong to stunt a Red Sox rally.

Seiya Suzuki propelled the Cubs to a 4-1 win on Friday with a three-run homer in the first inning. Suzuki now leads the National League with 80 RBIs, paired with his team-leading 26 home runs and .555 slugging percentage.

After snapping the Red Sox’ 10-game winning streak on Friday, the Cubs will look to push their own winning streak to four games on Saturday as they host Boston for the second game of a three-game set.

The Red Sox will look to rebound with Brayan Bello on the mound Saturday evening. The Cubs will counter with Shota Imanaga.

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Lineups

RED SOX (53-46): Refsnyder LF, Bregman 3B, Gonzalez 2B, Anthony RF, Story SS, Rafaela CF, Yoshida DH, Toro 1B, Wong C

Pitching: RHP Brayan Bello (6-3, 3.14 ERA)

CUBS (58-39): Busch 1B, Tucker RF, Suzuki DH, Crow-Armstrong CF, Happ LF, Swanson SS, Hoerner 2B, McGuire C, Brujan 3B

Pitching: LHP Shota Imanaga (6-3, 2.65 ERA)

Time: 7:15 p.m.

TV, radio: Fox, WEEI-FM 93.7

Red Sox vs. Imanaga: Jarren Duran 0-3, Ceddanne Rafaela 0-2, Rob Refsnyder 0-2, Connor Wong 1-3

Cubs vs. Bello: Jon Berti 0-2, Vidal Bruján 1-10, Ian Happ 0-3, Nico Hoerner 1-3, Carson Kelly 1-3, Seiya Suzuki 0-3, Kyle Tucker 1-5, Justin Turner 3-6

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Stat of the day: Boston’s pitching staff has gone 11 straight games allowing four runs or fewer.

Notes: Chicago’s 516 runs and 143 homers each rank second in the NL, trailing only the Dodgers. … Imanaga (6-3, 2.65 ERA) will look to prolong his stellar campaign for the Cubs on Saturday. A left hamstring strain placed the lefty on the injured list for nearly two months, but Imanaga has gone 3-1 with a 2.31 ERA in four starts since returning. … Imanaga allowed just one run in seven innings in Chicago’s first-half finale against the New York Yankees, a 4-1 Cubs’ win. In his lone career start against the Red Sox, Imanaga surrendered just one run in 6 1/3 innings in a 7-1 win in April 2024. … A winner in three consecutive starts, Bello is 3-0 with a 2.21 ERA in July. … Last time out, Bello allowed one run in 6 1/3 innings in a 4-1 victory over the Tampa Bay Rays. Bello has faced the Cubs once in his career, throwing six innings of three-run ball in an 8-3 win in July 2023.

Emma Healy can be reached at emma.healy@globe.com or on X @ByEmmaHealy.

The Chicago Cubs ended the Boston Red Sox’s 10-game winning streak on Friday, and our Red Sox vs. Cubs prediction expects the hosts to start a streak of their own.

The Cubs look for a series-clinching win tonight as -150 moneyline favorites at our best sports betting sites. First pitch from Wrigley Field in Chicago is set for 7:15 p.m. ET (FOX).

The Cubs have been one of MLB’s hottest teams offensively all season, but we are fading one of their hitters with our Red Sox vs. Cubs best bet. As a result, Dustin Saracini is also making this game one of the best NRFI bets today.

Red Sox vs. Cubs prediction: Cubs -1.5 (+135 via BetMGM ) ⭐⭐⭐⭐

Best Red Sox vs. Cubs player props: Matt Shaw Under 0.5 hits (+130 via bet365) ⭐⭐⭐⭐

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💰 Red Sox vs. Cubs prediction & best bet

✅ Red Sox vs. Cubs prediction: Cubs -1.5 (+135 via BetMGM)

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Boston hasn’t lost back-to-back games in their last 17 outings. However, Chicago has also won five straight as home favorites in interleague matchups, and I expect the hosts to roll to another comfortable win in my Red Sox vs. Cubs prediction.

Perhaps the All-Star break cooled down the Red Sox, who had averaged 7.1 runs per game, pitched to a 2.46 team ERA, and owned a plus-51 run differential in the 13 games leading up to the break.

Sharps clearly sided with the Cubs in spite of Boston’s 10-game winning streak to open the series, as Chicago went from -120 moneyline favorites to -135 at first pitch. It’s not hard to figure out why, either, as the Cubs entered the series ranked second in runs per game, third in defensive runs saved, third in home runs, third in stolen bases, and sixth in bullpen ERA.

Chicago’s biggest perceived weakness was its 18th-ranked starting pitching ERA (4.06). But that weakness is mitigated by today’s starter, Shota Imanaga, who has pitched to a 2.34 ERA in four starts since coming off the IL.

I am laying the 1.5 runs on the run line with my Red Sox vs. Cubs best bet, as National League teams have covered the runline in 12 of the last 17 interleague games.

💰 Best Red Sox vs. Cubs player props

✅ Best Red Sox vs. Cubs player prop: Matt Shaw Under 0.5 hits (+130 via bet365)

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The Cubs seem to have a glaring hole offensively at third base. With Matt Shaw being the player primarily manning that position, he leads our best Red Sox vs. Cubs player props.

Entering yesterday’s series opener, Matt Shaw had started 58 of Chicago’s 96 games at third base. Thus, he is a big reason why its third basemen ranked dead last in batting average (.199), home runs (1), and slugging percentage (.258), while ranking 29th in on-base percentage (.273).

Shaw ended a 0-for-22 slump with yesterday’s 1-for-3 performance, but these remain great odds on an ice-cold batter, and trumps the next-best odds (+125 at DraftKings) at any of our best sports betting apps.

💡 Expert MLB predictions

❓MLB betting FAQs

How do betting odds work?

Betting odds represent the probability of a specific outcome and determine how much money you can win on a bet. There are three main formats: American odds, Decimal odds, and Fractional odds. In the U.S., American odds are most common.

What is the run line in baseball?

The run line in baseball is a form of point spread betting unique to MLB. It typically sets a standard spread of 1.5 runs, meaning the favored team must win by at least two runs to cover the run line, while the underdog can lose by one run or win outright to cover.

What does moneyline mean in betting?

The moneyline in betting refers to a wager on which team or player will win the game outright, with no point spread involved. It’s the most straightforward type of sports bet—just pick the winner.

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